Where is celiac disease coming from and why?

  title={Where is celiac disease coming from and why?},
  author={Carlo Catassi},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={40 3},
  • C. Catassi
  • Published 1 March 2005
  • Medicine
  • Journal of pediatric gastroenterology and nutrition
In 1975, Charlotte Anderson, in her classic textbook on Paediatric Gastroenterology, wrote that ‘‘The typical child with celiac disease is usually fair-haired and blueeyed.’’ (1). Pioneer epidemiologic studies apparently enforced the concept of the ‘‘white face of CD’’ by reporting the highest world incidence of celiac disease (CD) from Western Ireland, Austria and Sweden (2). Like snow in the sun, these views melted away in the light of the subsequent developments of CD epidemiology. Sensitive… 

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The global burden of coeliac disease: opportunities and challenges

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Celiac disease and gluten-associated diseases.

  • S. Helms
  • Medicine
    Alternative medicine review : a journal of clinical therapeutic
  • 2005
This review explores the etiology and pathology of celiac disease, presents support for the relationship between gluten and other diseases, and provides effective screening and treatment protocols.

Molecular Structure Investigation of Gluten and Its Role in Celiac Disease

In this study, in addition to introducing the mechanism of celiac disease, the molecular structure of gluten and it interacts with HLA-DQ2 will be reviewed.

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"Early" vs. "late" diagnosis of celiac disease in two ethnic groups living in the same geographic area.

Compared the manifestations of celiac disease in children of both ethnic groups and questioned whether differences in presentation relate to degree of awareness for celiac Disease in each group, which varied markedly between both groups.

Prevalence of Celiac disease among children in Finland.

The presence of serum tissue transglutaminase and endomysial autoantibodies is predictive of small-bowel abnormalities indicative of celiac disease and there is a good correlation betweenAutoantibody positivity and specific HLA haplotypes.

Why is Celiac Disease So Common in Ireland?

The ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history are reviewed, and how these factors may have combined to result in a high frequency of celiac disease is considered.

The coeliac iceberg in Italy. A multicentre antigliadin antibodies screening for coeliac disease in school‐age subjects

These findings confirm that, in Italy, CD is one of the most common chronic disorders showing a wide and heterogeneous clinical spectrum and most CD cases remain undiagnosed unless actively searched.

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The screening protocol showed a very high prevalence of celiac disease for an urban area of Argentina that is ethnically similar to 90% of the general population of the country, and the heterogeneous clinical picture of new patients showed predominance of asymptomatic cases.

Celiac disease in Arabs.

The relatively high incidence of celiac disease in Jordanian children may be related to the large wheat consumption in this population (135 kg/head/year), and the late onset could berelated to the widespread prevalence of prolonged breast-feeding in Jordan and late introduction of cereals in children with late presentation.

Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study.

The results suggest that CD occurs frequently not only in patients with gastrointestinal symptoms, but also in first- and second-degree relatives and patients with numerous common disorders even in the absence of gastrointestinal symptoms.

Coeliac disease in Middle Eastern countries: a challenge for the evolutionary history of this complex disorder?

High prevalence of coeliac disease in a population‐based study from Western Australia: a case for screening?

The prevalence of coeliac disease is high in a rural Australian community, with a significant clustering of cases in the 30-50-years age range, with most patients are undiagnosed, and asymptomatic.

Celiac Disease in Children with Diarrhea Is More Frequent than Previously Suspected

CD is common among patients labeled as chronic diarrhea and in this subgroup, gluten-free diet may lead to a significant improvement in symptoms and be indicated in all patients being evaluated for chronic diarrhea.