When you can’t trust the DNA: RNA editing changes transcript sequences

  • Volker Knoop
  • Published 2010 in Cellular and Molecular Life Sciences

Abstract

RNA editing describes targeted sequence alterations in RNAs so that the transcript sequences differ from their DNA template. Since the original discovery of RNA editing in trypanosomes nearly 25 years ago more than a dozen such processes of nucleotide insertions, deletions, and exchanges have been identified in evolutionarily widely separated groups of the… (More)
DOI: 10.1007/s00018-010-0538-9

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