When natural selection gives gene function the cold shoulder.

Abstract

It is tempting to invoke organismal selection as perpetually optimizing the function of any given gene. However, natural selection can drive genic functional change without improvement of biochemical activity, even to the extinction of gene activity. Detrimental mutations can creep in owing to linkage with other selectively favored loci. Selection can… (More)
DOI: 10.1002/bies.201500083

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