When less is more: primary immunodeficiency with an autoinflammatory kick

@inproceedings{Giannelou2014WhenLI,
  title={When less is more: primary immunodeficiency with an autoinflammatory kick},
  author={Angeliki Giannelou and Qing Sheng Zhou and Daniel L. Kastner},
  booktitle={Current opinion in allergy and clinical immunology},
  year={2014}
}
PURPOSE OF REVIEW Next-generation sequencing is revolutionizing the molecular taxonomy of human disease. Recent studies of patients with unexplained autoinflammatory disorders reveal germline genetic mutations that target important regulators of innate immunity. RECENT FINDINGS Whole-exome analyses of previously undiagnosed patients have catalyzed the recognition of two new disease genes. First, a phenotypic spectrum, including livedo racemosa, fever with early-onset stroke, polyarteritis… CONTINUE READING
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