112 Citations
Evolutionary Developmental Biology: Homologous Regulatory Genes and
- Biology
- 2001
Traits in two species are classed as homologous when they are derived from a similar trait in a shared ancestor. Homology can exist at the levels of both anatomical structure and regulatory gene…
The developmental genetics of homology
- BiologyNature Reviews Genetics
- 2007
It is proposed that it is the historical continuity of gene regulatory networks rather than the expression of individual homologous genes that underlies the homology of morphological characters.
Deep homology: A view from systematics
- BiologyBioEssays : news and reviews in molecular, cellular and developmental biology
- 2010
Four examples – three from plants and one from animals – demonstrate that homologous developmental mechanisms can regulate a range of morphological relations including analogy, homoplasy and examples of uncertain homology.
The Role of Developmental Genetics in Understanding Homology and Morphological Evolution in Plants
- BiologyInternational Journal of Plant Sciences
- 2007
This work examines the role of APETALA3 and PISTILLATA homologs in the development of petaloid organs, and provides some guidelines for the critical examination of comparative gene expression data in the context of studying morphological innovations.
Evolutionary Developmental Biology: Homologous Regulatory Genes and Processes
- Biology
- 2001
Developmental genes provide a new way to identify homologous structures in animals by showing that both structures are specified by the same set of regulatory genes.
Birth, life and death of developmental control genes: New challenges for the homology concept
- BiologyTheory in Biosciences
- 2008
This article opts for a careful use of a limited and well-chosen set of terms describing gene relationships and function, rather than the inflationary production of novel terms that may seem to be precise, but whose obscurity hampers communication.
Birth, life and death of developmental control genes: new challenges for the homology concept.
- Biology
- 2005
Homology and ontogeny: pattern and process in comparative developmental biology
- BiologyTheory in Biosciences
- 2008
There is no ontogenetic homology “criterion”, the interface between development and homology is discussed, and a homology definition which includes similarity and complexity serves as a test for homology.
Homology in the Age of Developmental Genomics
- Biology
- 2015
The homology concept was introduced into pre-Darwinian evolutionary biology by Richard Owen as referring to “the same organ in different animals regardless of form and function” and was fully integrated into the Darwinian tradition through Lankester’s redefinition.
References
SHOWING 1-10 OF 53 REFERENCES
Developmental genetics and traditional homology.
- BiologyBioEssays : news and reviews in molecular, cellular and developmental biology
- 1996
It is argued that although developmental genetic data can help identify homologous structures, they are neither necessary nor sufficient, and do not in any case justify a new definition of homology.
Evolutionary dissociations between homologous genes and homologous structures.
- BiologyNovartis Foundation symposium
- 1999
The lack of a simple and consistent relationship between homologous genes and structures has important implications for understanding correlations between evolutionary changes at different levels of biological organization.
Developmental genetics and homology: a hierarchical approach.
- BiologyTrends in ecology & evolution
- 1997
A molecular approach to the evolution of vertebrate paired appendages.
- BiologyTrends in ecology & evolution
- 1996
Fossils, genes and the evolution of animal limbs
- BiologyNature
- 1997
The origin and diversification of fins, wings and other structures, long a focus of palaeontology, can now be approached through developmental genetics.
Mutations affecting segment number and polarity in Drosophila
- BiologyNature
- 1980
The phenotypes of the mutant embryos indicate that the process of segmentation involves at least three levels of spatial organization: the entire egg as developmental unit, a repeat unit with the length of two segments, and the individual segment.
Did homeodomain proteins duplicate before the origin of angiosperms, fungi, and metazoa?
- BiologyProceedings of the National Academy of Sciences of the United States of America
- 1997
The hypothesis that there was at least one duplication of homeobox genes before the origin of angiosperms, fungi, and metazoa is supported and suggests that these proteins had diverse functions early in the evolution of eukaryotes.
Radical alterations in the roles of homeobox genes during echinoderm evolution
- BiologyNature
- 1997
The expression domains in echinoderms of three important developmental regulatory genes ( distal-less, engrailed and orthodenticle ), all of which encode transcription factors that contain a homeodomain are reported, demonstrating the evolutionary lability of regulatory genes that are widely viewed as conservative.