When are reflux episodes symptomatic?

  title={When are reflux episodes symptomatic?},
  author={Giuseppe Portale and Jeffrey Peters and C C Hsieh and Anand P. Tamhankar and Mustafa A. Arain and Jayne Hagen and Steven R Demeester and Tom R. Demeester},
  journal={Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus},
  volume={20 1},
Careful scrutiny of pH recordings and symptom diaries in patients having 24-hour pH-metry reveals that most reflux episodes are asymptomatic. Although this observation is well known and long recognized, the explanation for why one reflux episode leads to symptoms and others do not is incompletely understood. Forty-four patients with chronic typical gastroesophageal reflux disease (GERD) symptoms referred for ambulatory pH testing were studied. Antisecretory medication was stopped 2 weeks prior… CONTINUE READING

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