When Checkpoints Fail

  title={When Checkpoints Fail},
  author={A. Paulovich and D. Toczyski and L. Hartwell},
  • A. Paulovich, D. Toczyski, L. Hartwell
  • Published 1997
  • Biology, Medicine
  • Cell
  • We would like to thank members of the Hartwell laboratory, especially Eric Foss, members of the Seattle project, Jim Roberts, Andrew Murray, and an annonymous reviewer for helpful comments on the manuscript. A. G. P. was supported by a Merck Distinguished Fellow Award and an MSTP training grant from the NIH. D. P. T. was supported by a fellowship from the Jane Coffin Childs Memorial Fund and an NIH training program in Cancer Research CA09437. L. H. H. is a Research Professor of the American… CONTINUE READING
    639 Citations
    Tumor surveillance via the ARF-p53 pathway.
    • C. Sherr
    • Biology, Medicine
    • Genes & development
    • 1998
    • 738
    • PDF
    Identification of a Functional Domain in a GADD45-mediated G2/M Checkpoint*
    • 88
    • PDF
    Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1.
    • 54
    • PDF
    Topoisomerase III Acts Upstream of Rad53p in the S-Phase DNA Damage Checkpoint
    • 71
    • PDF
    The MRE11-RAD50 Complex
    • 9


    A p53-dependent mouse spindle checkpoint
    • 698
    The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.
    • 246
    • PDF
    Testing the Role of p53 in the Expression of Genetic Instability and Apoptosis in Ataxia-telangiectasia.
    • 77
    Feedback control of mitosis in budding yeast
    • 1,232
    Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast.
    • 94
    • PDF
    The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint
    • 449
    • PDF
    RecA protein in the SOS response: milestones and mysteries.
    • 62