When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle.

  title={When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle.},
  author={Melisa Gualdr{\'o}n-L{\'o}pez and Ana Brennand and V. Hannaert and W. Qui{\~n}ones and A. C{\'a}ceres and F. Bringaud and J. Concepci{\'o}n and P. Michels},
  journal={International journal for parasitology},
  volume={42 1},
  • Melisa Gualdrón-López, Ana Brennand, +5 authors P. Michels
  • Published 2012
  • Biology, Medicine
  • International journal for parasitology
  • A characteristic, well-studied feature of the pathogenic protists belonging to the family Trypanosomatidae is the compartmentalisation of the major part of the glycolytic pathway in peroxisome-like organelles, hence designated glycosomes. Such organelles containing glycolytic enzymes appear to be present in all members of the Kinetoplastea studied, and have recently also been detected in a representative of the Diplonemida, but they are absent from the Euglenida. Glycosomes therefore probably… CONTINUE READING
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