When, how, and why a bone biopsy should be performed in patients with chronic kidney disease.

@article{Torres2014WhenHA,
  title={When, how, and why a bone biopsy should be performed in patients with chronic kidney disease.},
  author={Pablo Antonio Ure{\~n}a Torres and Jordi Bover and Sandro Mazzaferro and M C De vernejoul and M Cohen-solal},
  journal={Seminars in nephrology},
  year={2014},
  volume={34 6},
  pages={612-25}
}
In chronic kidney disease the excessive production of parathyroid hormone increases the bone resorption rate and leads to histologic bone signs of secondary hyperparathyroidism. However, in other situations, the initial increase in parathyroid hormone and bone remodeling may be slowed down excessively by a multitude of factors including age, ethnic origin, sex, and treatments such as vitamin D, calcium salts, calcimimetics, steroids, and so forth, leading to low bone turnover or adynamic bone… CONTINUE READING