Wheel running behavior is impaired by both surgical section and genetic absence of the mouse corpus callosum.

@article{Schalomon2002WheelRB,
  title={Wheel running behavior is impaired by both surgical section and genetic absence of the mouse corpus callosum.},
  author={P Melike Schalomon and Douglas L. Wahlsten},
  journal={Brain research bulletin},
  year={2002},
  volume={57 1},
  pages={27-33}
}
Mice lacking a corpus callosum (CC) often show little or no deficit on tests of behavior. This paper reports that on highly complex bimanual motor tasks, deficits can be found. The speed of running on a wheel with irregularly spaced rungs is reduced by both hereditary absence of the CC in 129 x BALB/c recombinant mice and surgical section of the CC in genetically normal B6D2F(2) mice. The effect of CC absence appears on measures most closely related to speed, no influence exists on the amount… CONTINUE READING