Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: involvement of rapid phospholipase C gamma 2 activation by Src family kinases.

@article{Ohmori2001WheatGA,
  title={Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: involvement of rapid phospholipase C gamma 2 activation by Src family kinases.},
  author={Tsukasa Ohmori and Yutaka Yatomi and Yuntao Wu and Makoto Osada and Kaneo Satoh and Yukio Ozaki},
  journal={Biochemistry},
  year={2001},
  volume={40 43},
  pages={12992-3001}
}
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) is a 130K transmembrane glycoprotein that belongs to the immunoglobulin gene superfamily and is expressed on the surface of hematological or vascular cells, including platelets and endothelial cells. Although the importance of this adhesion molecule in various cell-cell interactions is established, its function in platelets remains ill-defined. In the process of clarifying the mechanism by which the lectin wheat germ agglutinin (WGA… CONTINUE READING

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