What we do not know about ADHD… yet

  title={What we do not know about ADHD… yet},
  author={Bridget Kiely and Andrew Adesman},
  journal={Current Opinion in Pediatrics},
Purpose of review This article provides an overview of current controversies in attention-deficit/hyperactivity disorder (ADHD) research, with an emphasis on recent findings that are directly relevant to clinical practice. Recent findings Over the past few years, a number of studies have added key evidence to ongoing debates about the epidemiology, nosology, and treatment of ADHD. Although the causes of the rising prevalence of ADHD in the USA are still not fully understood, recent research… Expand
Why the Diagnosis of Attention Deficit Hyperactivity Disorder Matters
Strong partnerships between clinicians and patients with ADHD may be the best way to reduce the negative impacts of this disorder and more basic and clinical research will improve methods of diagnosis and information dissemination. Expand
The Utility of the CPT in the Diagnosis of ADHD in Individuals with Substance Abuse: A Systematic Review
The CPT might be sensitive to attentional deficits, but it lacks specificity for the classification of adult ADHD, SUD, or their comorbidity, and the CPT is thus not useful in discriminatingComorbid ADHD and SUD from either disorder alone. Expand
Contribution of Clinical Neuroimaging to the Understanding of the Pharmacology of Methylphenidate.
  • L. Zimmer
  • Psychology, Medicine
  • Trends in pharmacological sciences
  • 2017
The present review seeks to show how human molecular and functional imaging has contributed to determining not only the molecular targets of MPH, and the action kinetics of the various pharmaceutical forms available, but also the connectivity and brain networks activated by treatment. Expand
Managing Complexity: Exploring Decision Making on Medication by Young Adults with ADHD
For counselling at the pharmacy and by prescribers, it is important to be aware of the different factors that affect young adult patients’ decisions on whether to take ADHD medication or not, to understand reasons for non-adherence and to determine appropriate treatment for the individual patient. Expand
Pilot Study: An Ocular Biomarker for Diagnosis of Attention Deficit Hyperactivity Disorder
The different patterns of macular thickness might represent the immature cortical thickness of the brain in children with ADHD. Expand
Attention-deficit/hyperactivity disorder severity, diagnosis, & later academic achievement in a national sample.
Negative factors associated with an ADHD diagnosis may outweigh potential benefits for achievement among children with less severe ADHD-related behaviors, even those receiving treatment. Expand
Pupil Size Tracks Attentional Performance In Attention-Deficit/Hyperactivity Disorder
Pupil size correlated with the subjects’ performance and reaction time variability, two vastly studied indicators of attention, and was modulated by medication, suggesting that pupil size could serve as a biomarker in ADHD. Expand
Evaluation of motor proficiency and adiponectin in adolescent students with attention deficit hyperactivity disorder after high-intensity intermittent training
It is suggested that high intensity intermittent training improved physiological systems in ADHD population that leads to reduce risk factors for future development of comorbidities. Expand
Attentional shifting in children with developmental language disorder: A meta-analysis.
Results of moderator analyses reveal that deficits were found on set-shifting but not alternating tasks and that these deficits remained consistent whether researchers measure accuracy or response time switch costs to ascertain attentional shifting ability. Expand


Practitioner Review: What have we learnt about the causes of ADHD?
This review critically considers putative risk factors with a focus on genetics and selected environmental risks, examines their relationships with ADHD and discusses the likelihood that these risks are causal as well as some of the main implications. Expand
ADHD pharmacogenetics across the life cycle: New findings and perspectives
  • E. M. Bruxel, G. C. Akutagava-Martins, +4 authors L. Rohde
  • Medicine
  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • 2014
A systematic review of the literature on ADHD pharmacogenetics is presented to provide a critical discussion of the existent findings, new approaches, limitations, and recommendations for future research. Expand
Evaluating the Evidence For and Against the Overdiagnosis of ADHD
There does not appear to be sufficient justification for the conclusion that ADHD is systematically overdiagnosed, and this conclusion is generally not reflected in public perceptions or media coverage of ADHD. Expand
A Review of Neurofeedback Treatment for Pediatric ADHD
It is concluded that NF for pediatric ADHD can be currently considered as “probably efficacious” and based on the results and methodologies of published studies, this review concludes. Expand
The Second Attention Disorder? Sluggish Cognitive Tempo vs. Attention-Deficit/Hyperactivity Disorder: Update for Clinicians
It seems likely that a constellation of characteristic features of SCT may form the criteria for a newly defined childhood disorder in the foreseeable future, provided limitations in the extant findings can be addressed by future research. Expand
Effect of stimulants on height and weight: a review of the literature.
Treatment with stimulants in childhood modestly reduced expected height and weight and more work is needed to clarify the effects of continuous treatment from childhood to adulthood. Expand
Complementary and alternative therapies for children and adolescents with ADHD
Most complementary and alternative treatments do not have adequate research to recommend their use in children with ADHD, and physicians should be aware of the many CAM treatment options and the research surrounding them. Expand
Is ADHD diagnosed in accord with diagnostic criteria? Overdiagnosis and influence of client gender on diagnosis.
It is suggested that overdiagnosis of ADHD occurs in clinical routine and that the patient's gender influences diagnosis considerably, and thorough diagnostic training might help therapists to avoid these biases. Expand
Do Stimulants Protect Against Psychiatric Disorders in Youth With ADHD? A 10-Year Follow-up Study
Evidence is found that stimulant treatment decreases the risk for subsequent comorbid psychiatric disorders and academic failure in youth with ADHD. Expand
Attention Deficit Hyperactivity Disorder. A Handbook for Diagnosis and Treatment
Psychiatric practitioners, seasoned and new alike, should welcome the recent publication of the third edition of Russell Barkley’s classic textbook on attention-deficit/hyperactivity disorder (ADHD).Expand