What to do when SSRIs fail: eight strategies for optimizing treatment of panic disorder.

@article{Zamorski2002WhatTD,
  title={What to do when SSRIs fail: eight strategies for optimizing treatment of panic disorder.},
  author={M A Zamorski and Ronald C Albucher},
  journal={American family physician},
  year={2002},
  volume={66 8},
  pages={1477-84}
}
Selective serotonin reuptake inhibitors (SSRIs) are the drug of choice for treatment of patients with panic disorder. Most patients have a favorable response to SSRI therapy; however, 30 percent will not be able to tolerate these drugs or will have an unfavorable or incomplete response. Strategies to improve management of such patients include optimizing SSRI dosing (starting at a low dose and slowly increasing the dose to reach the target dose) and ensuring an adequate trial before switching… CONTINUE READING