What the cell "sees" in bionanoscience.

  title={What the cell "sees" in bionanoscience.},
  author={Dorota Walczyk and Francesca Baldelli Bombelli and Marco P. Monopoli and Iseult Lynch and Kenneth A. Dawson},
  journal={Journal of the American Chemical Society},
  volume={132 16},
What the biological cell, organ, or barrier actually "sees" when interacting with a nanoparticle dispersed in a biological medium likely matters more than the bare material properties of the particle itself. Typically the bare surface of the particle is covered by several biomolecules, including a select group of proteins drawn from the biological medium. Here, we apply several different methodologies, in a time-resolved manner, to follow the lifetime of such biomolecular "coronas" both in situ… CONTINUE READING
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