What proportion of episodes of gonorrhoea and chlamydia becomes symptomatic?

@article{Korenromp2002WhatPO,
  title={What proportion of episodes of gonorrhoea and chlamydia becomes symptomatic?},
  author={Eline L Korenromp and Mondastri Korib Sudaryo and Sake J. de Vlas and Ronald H Gray and Nelson K Sewankambo and David Serwadda and Maria J Wawer and J. Dik F. Habbema},
  journal={International Journal of STD \& AIDS},
  year={2002},
  volume={13},
  pages={101 - 91}
}
The effectiveness of syndromic treatment as an STD control strategy depends on the proportion of episodes which become symptomatic; few studies have measured this directly. We estimated these proportions for gonorrhoea (NG) and chlamydia (CT), synthesizing data on the point prevalence of self-reported discharge and dysuria among infected cases in rural Uganda, the durations of symptoms, incubation period and asymptomatic episodes, and the effect of treatment on symptom duration. Estimated… 

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References

SHOWING 1-10 OF 62 REFERENCES
Determinants of reinfection with Chlamydia trachomatis.
TLDR
As well as targeting sexually active adolescents, prevention programs should recommend repeat testing for all women with prior chlamydial infection, irrespective of age, because issues related to personal control of health may modify risk for infection.
Are chlamydial infections the most prevalent venereal disease?
TLDR
In both population groups, chlamydiae were more prevalent than herpesviruses and chlamydial infection was associated much more commonly with cervicitis than with vaginitis only.
Chlamydia trachomatis urethral infections in men. Prevalence, risk factors, and clinical manifestations.
TLDR
Asymptomatic urethral infections in men eventually contribute to chlamydial infections in women, and culture screening for their detection appears warranted in high-risk populations.
Clinical spectrum of infection with Neisseria gonorrhoeae.
: The traditional view that infections with Neisseria gonorrhoeae are predominantly symptomatic in men and predominantly asymptomatic in women has arisen from studies conducted in sexually
Epidemiology of venereal urethritis: comparison of gonorrhea and nongonococcal urethritis.
  • J. McCutchan
  • Medicine, Biology
    Reviews of infectious diseases
  • 1984
TLDR
Data from individual clinics suggest that incidence of both Gonorrhea and NGU has remained stable over the past decade, and marked socioeconomic and racial differences in both relative incidence of and susceptibility to NGU and GU have been found repeatedly but are unexplained.
Gonorrhoea in men: clinical and diagnostic aspects.
TLDR
The incubation and infectious period of urethral gonorrhoea has increased compared with previous studies and that symptoms have altered, suggesting that the features of gonococcal infection in men in the 1990s have changed.
Epidemiology of sexually transmitted Chlamydia trachomatis infections.
TLDR
There is a need to define the prevalence and incidence of chlamydial infection in different populations so that high risk groups can be identified and targeted for prevention programs and the most efficient approach to managing chlamYDial infection may be provided by a vaccine.
Unrecognized sexually transmitted infections in rural South African women: a hidden epidemic.
TLDR
Estimates of the prevalence, on any given day, of STIs among women in rural South Africa and the proportion who are asymptomatic, symptomatic but not seeking care, and symptomatic and seeking care are presented.
The transmission dynamics of gonorrhoea: modelling the reported behaviour of infected patients from Newark, New Jersey.
TLDR
Screening and contact-tracing to identify asymptomatic infections in both men and women will be more effective in reaching those who maintain the infection within the community rather than simply treating symptomatic cases.
...
...