What problems of physics and astrophysics seem now to be especially important and interesting ( thirty years later , already on the verge of XXI century ) ?

@inproceedings{GinzburgWhatPO,
  title={What problems of physics and astrophysics seem now to be especially important and interesting ( thirty years later , already on the verge of XXI century ) ?},
  author={Vitaly L Ginzburg}
}