What makes vessels grow with exercise training?

@article{Prior2004WhatMV,
  title={What makes vessels grow with exercise training?},
  author={Barry M. Prior and Hsiao Tung Yang and Ronald L. Terjung},
  journal={Journal of applied physiology},
  year={2004},
  volume={97 3},
  pages={
          1119-28
        }
}
Exercise and muscle contractions create a powerful stimulus for structural remodeling of the vasculature. An increase in flow velocity through a vessel increases shear stress, a major stimulus for enlargement of conduit vessels. This leads to an endothelial-dependent, nitric oxide-dependent enlargement of the vessel. Increased flow within muscle, in the absence of contractions, leads to an enhanced capillarity by intussusceptive angiogenesis, a process of capillary splitting by intraluminal… CONTINUE READING

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Acute upregulation of PGC-1α mRNA correlates with training-induced increases in SDH activity in human skeletal muscle.

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