What makes a champion? Explaining variation in human athletic performance
@article{Brutsaert2006WhatMA, title={What makes a champion? Explaining variation in human athletic performance}, author={Tom D. Brutsaert and Esteban Juan Parra}, journal={Respiratory Physiology \& Neurobiology}, year={2006}, volume={151}, pages={109-123} }
Figures from this paper
77 Citations
The genetic basis of human athletic performance. Why are psychological components so often overlooked?
- BiologyThe Journal of physiology
- 2008
Emerging evidence attests that research on the genetic basis of ‘physiological phenotypes’ might provide additional, valuable elements to determine ‘advantageous’ polygenic profiles.
Genes, athlete status and training -- An overview.
- BiologyMedicine and sport science
- 2009
The preliminary data suggest an opportunity to use some of the genetic markers linked to elite athlete status in an individually tailored prescription of lifestyle/exercise for health and sports performance.
Genetics and sports.
- BiologyBritish medical bulletin
- 2010
Since exercise training regulates the expression of genes encoding various enzymes in muscle and other tissues, genetic research in sports will help clarify several aspects of human biology and physiology, such as RNA and protein level regulation under specific circumstances.
Genetic Polymorphisms Associated with Elite Athlete Status
- Biology
- 2015
This chapter introduces some of the studies focusing on mitochondrial DNA polymorphism and the two most studied nuclear DNA polymorphisms, namely angiotensin I-converting enzyme (ACE) and α-actinin-3 (ACTN3) polymorphisms.
Genomics of elite sporting performance: what little we know and necessary advances.
- BiologyAdvances in genetics
- 2013
Genes, Environment and Sport Performance
- PsychologySports medicine
- 2007
It is argued that, due to inherent human degeneracy, there are many different trajectories to achieving elite Athletic Performance, and the concept of degeneracy provides a basis for understanding why each of the major interacting constraints might act in a compensatory manner on the acquisition of elite athletic performance.
The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes
- BiologyHuman Genetics
- 2009
Investigating individually and in combination the association of common metabolic gene polymorphisms with endurance athlete status, the proportion of slow-twitch muscle fibers and maximal oxygen consumption suggests that the likelihood of becoming an elite endurance athlete depends on the carriage of a high number of endurance-related alleles.
Genetic and molecular aspects of sport performance
- Biology
- 2011
The full range of genetic variation responsible for human variability in athletic per-formance is likely to include both rare and com-mon polymorphisms, and many such variants can and will be found.
Sports genomics: Current state of knowledge and future directions
- Biology
- 2012
This review summarizes the evidence and mechanistic insights on the associations between DNA polymorphisms and athletic performance and identifies 20 genetic markers that have shown positive associations with athlete status in at least two studies.
Genetic studies of elite athlete status
- Biology
- 2013
It is probable that the genes studied here are not the resulting variants responsible for the phenotypes of interest, despite the associations reported by previous candidate-gene studies in other sports.
References
SHOWING 1-10 OF 162 REFERENCES
Genes and human elite athletic performance
- BiologyHuman Genetics
- 2005
A review of the evidence that has accumulated over the last three decades for a strong genetic influence on human physical performance, with an emphasis on two sets of physical traits, viz. cardiorespiratory and skeletal muscle function, which are particularly important for performance in a variety of sports.
What makes an endurance athlete world-class? Not simply a physiological conundrum.
- EducationComparative biochemistry and physiology. Part A, Molecular & integrative physiology
- 2003
The search for genotypes that underlie human performance phenotypes.
- EducationComparative biochemistry and physiology. Part A, Molecular & integrative physiology
- 2003
Genetics of fitness and physical performance
- Biology
- 1997
This essential compendium reviews the past 25 years of accumulated evidence on the genetic basis of health- and performance-related fitness phenotypes and offers readers new opportunities to better understand atherosclerosis, noninsulin dependent diabetes, obesity, and hypertension.
Heritability of running economy: a study made on twin brothers
- MedicineEuropean Journal of Applied Physiology and Occupational Physiology
- 1998
A genetic component for markers of anaerobic metabolism was present in RE and in maximal oxygen uptake in a group of 32 male twins, all sportsmen with similar perinatal and environmental backgrounds.
Heritability of explosive power and anaerobic capacity in humans
- MedicineEuropean Journal of Applied Physiology
- 2002
The most relevant findings were significant HI values for many of the variables studied; the HI values of the parameters used to evaluate explosive power were higher than those of lactic acid capacity and thirdly, the HI of certain variables from different tests measuring, in theory, similar qualities, were different.
Familial resemblance for VO2max in the sedentary state: the HERITAGE family study.
- PsychologyMedicine and science in sports and exercise
- 1998
The hypothesis of maternal inheritance, with the father's contribution being environmental, was found to fit the data with estimates of maternal heritability, potentially associated with mitochondrial inheritance, reaching about 30%.
Genes and athletes.
- BiologyAdolescent medicine
- 2002
This chapter reviews selective aspects of genotype influence on sport performance, uses and misuses of genetic technology, and ethical as well as legal dilemmas.
The human gene map for performance and health-related fitness phenotypes.
- MedicineMedicine and science in sports and exercise
- 2001
The aim of this paper is to describe the first human gene map for physical performance and health-related fitness traits based on the papers published until the end of 2000. Studies of candidate…