What made sesquiterpene lactones reach cancer clinical trials?

@article{Ghantous2010WhatMS,
  title={What made sesquiterpene lactones reach cancer clinical trials?},
  author={Akram Ghantous and Hala Gali-Muhtasib and Heikki Vuorela and Najat A Saliba and Nadine D Darwiche},
  journal={Drug discovery today},
  year={2010},
  volume={15 15-16},
  pages={668-78}
}
Sesquiterpene lactones (SLs) are plant-derived compounds often used in traditional medicine against inflammation and cancer. This review focuses on the chemical and biological properties of SLs that lead to enhanced anticancer and anti-inflammatory effects. The chemical properties comprise alkylating center reactivity, lipophilicity, and molecular geometry… CONTINUE READING