What is wrong with the allosteric disulfide bond hypothesis?

@article{Bach2009WhatIW,
  title={What is wrong with the allosteric disulfide bond hypothesis?},
  author={Ronald R Bach and Dougald M Monroe},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2009},
  volume={29 12},
  pages={
          1997-8
        }
}
Series Editor: Nigel Mackman Mark B. Taubman ATVB In Focus Tissue Factor: Past, Present, and Future Initial models of coagulation postulated a strict separation of the initiator of coagulation, tissue factor (TF), from the coagulation factors in blood. More recent studies have shown low but detectable levels of TF in blood1 (reviewed in2). This suggests that TF activity is under some level of control beyond simple expression levels. One mechanism of control is suggested by the observation… CONTINUE READING

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Protein disulfide isomerase in thrombosis and vascular inflammation.

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