What is the potential of avirulent influenza viruses to complement a cleavable hemagglutinin and generate virulent strains?

Abstract

A large pool of avirulent influenza viruses are maintained in the wild ducks and shorebirds of the world, but we know little about their potential to become virulent. It is well established that the hemagglutinin (HA) is pivitol in determining virulence and that a constellation of other genes is also necessary (R. Rott, M. Orlich, and C. Scholtissek, 1976… (More)

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