What is the optimum number of CD34+ peripheral blood stem cells for an autologous transplant?

@article{Jillella2004WhatIT,
  title={What is the optimum number of CD34+ peripheral blood stem cells for an autologous transplant?},
  author={Anand P. Jillella and Celalettin Ustun},
  journal={Stem cells and development},
  year={2004},
  volume={13 6},
  pages={
          598-606
        }
}
There is a wide variation in the number of CD34+ cells infused for an autologous transplantation. While the minimum number of hematopoietic stem cells for a successful transplantation has been established, there is no definite information on the optimum number or the maximum number of stem cells. It is generally agreed that a minimum dose of 2.5 x 10(6) CD34+ cells is necessary for successful engraftment. Although engraftment of neutrophils and platelets is achieved at that dose, it is delayed… CONTINUE READING

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