What is the clinically relevant change on the ADAS-Cog?

@article{Schrag2012WhatIT,
  title={What is the clinically relevant change on the ADAS-Cog?},
  author={Anette Schrag and Jonathan M. Schott},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2012},
  volume={83 2},
  pages={171-3}
}
OBJECTIVE To establish the minimal clinically relevant change (MCRC) on the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) for patients with mild Alzheimer's disease (AD). DESIGN Cohort study. SETTING 59 recruiting sites for the Alzheimer's Disease Neuroimaging Initiative. PATIENTS Outpatients with AD in the Alzheimer's Disease Neuroimaging Initiative. MAIN OUTCOME MEASURES The authors applied anchor-based MCRC methodology comparing ADAS-Cog change against clinicians… CONTINUE READING
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