What is the best treatment to decrease pro-inflammatory cytokine release in acute skeletal muscle injury induced by trauma in rats: low-level laser therapy, diclofenac, or cryotherapy?

@article{Almeida2013WhatIT,
  title={What is the best treatment to decrease pro-inflammatory cytokine release in acute skeletal muscle injury induced by trauma in rats: low-level laser therapy, diclofenac, or cryotherapy?},
  author={Patricia E. de Almeida and Shaiane Silva Tomazoni and L. Frigo and Paulo de Tarso Camillo de Carvalho and Adriane Aver Vanin and Larissa Aline Santos and Gianna M{\'o}es Albuquerque-Pontes and Thiago De Marchi and Olga Sergueevna Tairova and Rodrigo Labat Marcos and Rodrigo {\'A}lvaro Brand{\~a}o Lopes-Martins and Ernesto Cesar Pinto Leal-Junior},
  journal={Lasers in Medical Science},
  year={2013},
  volume={29},
  pages={653-658}
}
Currently, treatment of muscle injuries represents a challenge in clinical practice. In acute phase, the most employed therapies are cryotherapy and nonsteroidal anti-inflammatory drugs. In the last years, low-level laser therapy (LLLT) has becoming a promising therapeutic agent; however, its effects are not fully known. The aim of this study was to analyze the effects of sodium diclofenac (topical application), cryotherapy, and LLLT on pro-inflammatory cytokine levels after a controlled model… CONTINUE READING

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In acute phase , the most employed therapies are cryotherapy and nonsteroidal anti - inflammatory drugs .
In acute phase , the most employed therapies are cryotherapy and nonsteroidal anti - inflammatory drugs .
Assessment of interleukin-1β and interleukin-6 ( IL-1β and IL-6 ) and tumor necrosis factor - alpha ( TNF-α ) levels was performed at 6 h after trauma employing enzyme - linked immunosorbent assay method .
Assessment of interleukin-1β and interleukin-6 ( IL-1β and IL-6 ) and tumor necrosis factor - alpha ( TNF-α ) levels was performed at 6 h after trauma employing enzyme - linked immunosorbent assay method .
In acute phase , the most employed therapies are cryotherapy and nonsteroidal anti - inflammatory drugs .
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