What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial.

@article{Lee2017WhatIT,
  title={What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial.},
  author={Sung Yup Lee and Suri Chong and Dhanasekaraprabu Balasubramanian and Young Gon Na and Tae Kyun Kim},
  journal={Clinical orthopaedics and related research},
  year={2017},
  volume={475 8},
  pages={
          1987-1996
        }
}
BACKGROUND TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood loss after TKA. Numerous clinical trials have documented the efficacy and safety of intravenous (IV) or intraarticular (IA) use of tranexamic acid. Combined administration of tranexamic acid also has been suggested; however, there is no consensus regarding the ideal route of tranexamic acid administration. QUESTIONS/PURPOSES (1) To compare the efficacy of tranexamic acid in terms of total… CONTINUE READING