What is pH regulation, and why do cancer cells need it?

@inproceedings{Swietach2018WhatIP,
  title={What is pH regulation, and why do cancer cells need it?},
  author={Pawel Swietach},
  booktitle={Cancer and Metastasis Reviews},
  year={2018}
}
Metabolism is a continuous source of acids. To keep up with a desired metabolic rate, tumors must establish an adequate means of clearing their acidic end-products. This homeostatic priority is achieved by various buffers, enzymes, and transporters connected through the common denominator of H+ ions. Whilst this complexity is proportionate to the importance of adequate pH control, it is problematic for developing an intuition for tracking the route taken by acids, assessing the relative… CONTINUE READING

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