What is learned during opiate withdrawal conditioning? Evidence for a cue avoidance model

@article{Mucha1991WhatIL,
  title={What is learned during opiate withdrawal conditioning? Evidence for a cue avoidance model},
  author={Ronald F. Mucha},
  journal={Psychopharmacology},
  year={1991},
  volume={104},
  pages={391-396}
}
How conditioned opiate withdrawal gives rise to avoidance behaviour was examined using a defensive burying procedure in rats made dependent with a morphine pellet. The subjects underwent withdrawal precipitated by naloxone (0.1 mg/kg, SC) on two or three occasions in a box containing only a small object. When exposed to the object in the presence of sawdust one or more days later, the subjects avoided contact and buried this object, i.e., pushed and piled the sawdust against it. The behaviour… CONTINUE READING

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Opiate withdrawal-produced dysphoria: a taste preference conditioning model

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Conditioned defensive burying : a biological and cognitive approach to avoidance learning

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Conditioned defensive burying: a biological and cognitive approach to avoidance learning. In: Mellgren RL (ed) Animal cognition and behaviour

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