What is changing in the natural history of chronic lymphocytic leukemia?

  title={What is changing in the natural history of chronic lymphocytic leukemia?},
  author={Stefano Molica and Domenico Levato},
  volume={86 1},
BACKGROUND AND OBJECTIVES In the last few years there has been a trend towards an improvement in overall survival of patients with chronic lymphocytic leukemia (CLL). Studies based on tumor registries of the general population or including patients referred to hematologic institutions have analyzed reasons for these changes. However, results need to be validated on independent series. DESIGN AND METHODS We retrospectively evaluated 518 CLL patients diagnosed at our institution between January… CONTINUE READING


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