What is a resistance gene? Ranking risk in resistomes

  title={What is a resistance gene? Ranking risk in resistomes},
  author={Jos{\'e} L Mart{\'i}nez and Teresa M. Coque and Fernando Baquero},
  journal={Nature Reviews Microbiology},
Metagenomic studies have shown that antibiotic resistance genes are ubiquitous in the environment, which has led to the suggestion that there is a high risk that these genes will spread to bacteria that cause human infections. If this is true, estimating the real risk of dissemination of resistance genes from environmental reservoirs to human pathogens is therefore very difficult. In this Opinion article, we analyse the current definitions of antibiotic resistance and antibiotic resistance… CONTINUE READING
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