What is Intervertebral Disc Degeneration, and What Causes It?

@article{Adams2006WhatII,
  title={What is Intervertebral Disc Degeneration, and What Causes It?},
  author={Michael A. Adams and Peter J. Roughley},
  journal={Spine},
  year={2006},
  volume={31},
  pages={2151-2161}
}
Study Design. Review and reinterpretation of existing literature. Objective. To suggest how intervertebral disc degeneration might be distinguished from the physiologic processes of growth, aging, healing, and adaptive remodeling. Summary of Background Data. The research literature concerning disc degeneration is particularly diverse, and there are no accepted definitions to guide biomedical research, or medicolegal practice. Definitions. The process of disc degeneration is an aberrant, cell… 

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