What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues.

Abstract

Cell membranes can be transiently permeabilized under application of electric pulses. This treatment allows hydrophilic therapeutic molecules, such as anticancer drugs and DNA, to enter into cells and tissues. This process, called electropermeabilization or electroporation, has been rapidly developed over the last decade to deliver genes to tissues and… (More)
DOI: 10.1007/s12033-008-9121-0

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Cite this paper

@article{Escoffre2009WhatI, title={What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues.}, author={Jean-michel Escoffre and Thomas Portet and Luc Wasungu and Justin Teissi{\'e} and David Dean and Marie-Pierre Rols}, journal={Molecular biotechnology}, year={2009}, volume={41 3}, pages={286-95} }