What if I don't treat my PSA-detected prostate cancer? Answers from three natural history models.

@article{Gulati2011WhatII,
  title={What if I don't treat my PSA-detected prostate cancer? Answers from three natural history models.},
  author={Roman Gulati and Elisabeth M. Wever and A. Tsodikov and David F Penson and Lurdes Y. T. Inoue and Jeffrey Katcher and S C Lee and Eveline A M Heijnsdijk and Gerrit Draisma and Harry J. de Koning and Ruth Etzioni},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2011},
  volume={20 5},
  pages={740-50}
}
BACKGROUND Making an informed decision about treating a prostate cancer detected after a routine prostate-specific antigen (PSA) test requires knowledge about disease natural history, such as the chances that it would have been clinically diagnosed in the absence of screening and that it would metastasize or lead to death in the absence of treatment. METHODS We use three independently developed models of prostate cancer natural history to project risks of clinical progression events and… CONTINUE READING

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