What has been learned about the cardiovascular effects of matrix metalloproteinases from mouse models?

@article{Janssens2006WhatHB,
  title={What has been learned about the cardiovascular effects of matrix metalloproteinases from mouse models?},
  author={Stefan P. Janssens and Henri Roger Lijnen},
  journal={Cardiovascular research},
  year={2006},
  volume={69 3},
  pages={585-94}
}
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes responsible for extracellular protein degradation in the cardiovascular system. Originally known to play pivotal roles in tissue morphogenesis and wound healing, they have been shown to participate in the complex remodeling processes in blood vessels and the myocardium. The biological activity of MMPs is regulated at different levels: (1) gene expression, (2) activation of precursor proenzyme forms by other MMPs or non-MMP… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 99 references

Matrix metalloproteinases and collagen ultrastructure in moderate myocardial ischemia and reperfusion in vivo.

American journal of physiology. Heart and circulatory physiology • 2000
View 6 Excerpts
Highly Influenced

Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons • 2005
View 2 Excerpts

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