What generates whisking? Focus on: "The whisking rhythm generator: a novel mammalian network for the generation of movement".
@article{CastroAlamancos2007WhatGW,
title={What generates whisking? Focus on: "The whisking rhythm generator: a novel mammalian network for the generation of movement".},
author={Manuel A. Castro-Alamancos},
journal={Journal of neurophysiology},
year={2007},
volume={97 3},
pages={
1883-4
}
}A central goal of neuroscience is to explain how neural networks generate organized and repetitive motor patterns, such as active whisking used by rodents to navigate the environment. Whisking consists of fast rhythmic ellipsoid vibrissae movements through the air and over objects at between 4 andÂ
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Genetic Control of a Central Pattern Generator: Rhythmic Oromotor Movement in Mice Is Controlled by a Major Locus near Atp1a2
- BiologyPloS one
- 2012
Fluid licking in mice is a rhythmic behavior that is controlled by a central pattern generator (CPG) located in a complex of brainstem nuclei, and sequence variants in or near Apt1a2 strongly modulate expression of the cognate mRNA in multiple brain regions are strongly modulated.
References
SHOWING 1-10 OF 23 REFERENCES
The whisking rhythm generator: a novel mammalian network for the generation of movement.
- BiologyJournal of neurophysiology
- 2007
In vivo, the tonic activity of putative serotonergic premotoneurons is positively correlated with the frequency of whisking evoked by cortical stimulation, and these results support the hypothesized novel mammalian mechanism for movement generation in the vibrissa motor system.
Whisker motor cortex ablation and whisker movement patterns
- Biology, PsychologySomatosensory & motor research
- 2003
While the lesion did not abolish whisking, it significantly disrupted whisking kinematics, coordination, and temporal organization, suggesting that the observed deficits reflect an imbalance in cortical inputs to a brainstem central pattern generator.
Whisker Deafferentation and Rodent Whisking Patterns: Behavioral Evidence for a Central Pattern Generator
- Biology, PsychologyThe Journal of Neuroscience
- 2001
Optoelectronic instrumentation was used to obtain high-resolution records of the movement trajectories of individual whiskers in rats whose heads were fixed to isolate their exploratory whisking from exafferent inputs, providing strong behavioral evidence for a whisking CPG.
Vibrissa myoclonus (rhythmic retractions) driven by resonance of excitatory networks in motor cortex.
- BiologyJournal of neurophysiology
- 2006
The results demonstrate that rhythmic motor cortex output is capable of driving vibrissa movements on a cycle-by-cycle basis.
Biological Pattern Generation: The Cellular and Computational Logic of Networks in Motion
- BiologyNeuron
- 2006
Neural substrates of two different rhythmical vibrissal movements in the rat
- Biology, PsychologyNeuroscience
- 1984
The relationship of vibrissal motor cortex unit activity to whisking in the awake rat.
- Biology, PsychologySomatosensory & motor research
- 1996
Findings support a role for vibrissal motor cortex in the initiation and modulation of the overall level of mystacial pad muscular output, but not in the generation of bursts of EMG activity responsible for individual whisking sweeps.
Active sensation: insights from the rodent vibrissa sensorimotor system
- BiologyCurrent Opinion in Neurobiology
- 2006
