What does the MADRS mean? Equipercentile linking with the CGI using a company database of mirtazapine studies.

@article{Leucht2017WhatDT,
  title={What does the MADRS mean? Equipercentile linking with the CGI using a company database of mirtazapine studies.},
  author={Stefan Leucht and Hein Fennema and Rolf R. Engel and Marion Kaspers-Janssen and Peter Lepping and Armin Szegedi},
  journal={Journal of affective disorders},
  year={2017},
  volume={210},
  pages={287-293}
}
BACKGROUND Little is known about the clinical relevance of the Montgomery Asberg Depression Rating Scale (MADRS) total scores. It is unclear how total scores translate into clinical severity, or how commonly used measures for response (reduction from baseline of ≥50% in the total score) translate into clinical relevance. Moreover, MADRS based definitions of remission vary. METHODS We therefore compared: a/ the MADRS total score with the Clinical Global Impression - Severity Score (CGI-S) b… CONTINUE READING