What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues?

@article{Arnold2009WhatDT,
  title={What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues?},
  author={Arthur P. Arnold and Xuqi Chen},
  journal={Frontiers in neuroendocrinology},
  year={2009},
  volume={30 1},
  pages={1-9}
}
The "four core genotypes" (FCG) model comprises mice in which sex chromosome complement (XX vs. XY) is unrelated to the animal's gonadal sex. The four genotypes are XX gonadal males or females, and XY gonadal males or females. The model allows one to measure (1) the differences in phenotypes caused by sex chromosome complement (XX vs. XY), (2) the differential effects of ovarian and testicular secretions, and (3) the interactive effects of (1) and (2). Thus, the FCG model provides new… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 132 extracted citations

Similar Papers

Loading similar papers…