What do microarrays really tell us about M. tuberculosis?

  title={What do microarrays really tell us about M. tuberculosis?},
  author={Sharon L. Kendall and Stuart C. G. Rison and Farahnaz Movahedzadeh and Rosangela Frita and Neil G. Stoker},
  journal={Trends in microbiology},
  volume={12 12},
Bacterial pathogens adapt to their host environments to a large extent through switching on complex transcriptional programmes, and whole-genome microarray experiments promise to reveal this complexity. There has been a recent burst of articles reporting transcriptome analyses of Mycobacterium tuberculosis, including for the first time studies in macrophages and mice. We review gene expression reports, and compare them with each other and with microarray-based gene essentiality studies… CONTINUE READING

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