What distinguishes adipose tissue of severely obese humans who are insulin sensitive and resistant?

@article{Xu2013WhatDA,
  title={What distinguishes adipose tissue of severely obese humans who are insulin sensitive and resistant?},
  author={Xiaobin Xu and Walter J. Pories and Lynis G Dohm and Neil Bertrand Ruderman},
  journal={Current opinion in lipidology},
  year={2013},
  volume={24 1},
  pages={49-56}
}
PURPOSE OF REVIEW Despite a strong correlation between obesity and insulin resistance, 25% of severely obese (BMI >40) individuals are insulin sensitive. In this review, we will examine the factors in adipose tissue that distinguish the two groups, as well as reasons for believing the insulin-sensitive group will be less disease prone. RECENT FINDINGS Obesity has been linked to the metabolic syndrome with an increase in visceral (intra-abdominal) compared to subcutaneous fat. Recent studies… CONTINUE READING
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