What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression.

@article{Gaynes2009WhatDS,
  title={What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression.},
  author={Bradley N. Gaynes and Diane Warden and Madhukar H. Trivedi and Stephen R. Wisniewski and Maurizio Fava and A. John Rush},
  journal={Psychiatric services},
  year={2009},
  volume={60 11},
  pages={1439-45}
}
The authors provide an overview of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study (www.star-d.org), a large-scale practical clinical trial to determine which of several treatments are the most effective "next-steps" for patients with major depressive disorder whose symptoms do not remit or who cannot tolerate an initial treatment and, if needed, ensuing treatments. Entry criteria were broadly defined and inclusive, and patients were enrolled from psychiatric and… CONTINUE READING
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