What causes the onset of psychosis?

  title={What causes the onset of psychosis?},
  author={Matthew Broome and James Woolley and Paul Tabraham and Louise Johns and Elvira Bramon and Graham K. Murray and Carmine M Pariante and Philip K. McGuire and Robin M. Murray},
  journal={Schizophrenia research},
  volume={79 1},
It has become increasingly clear that the simple neurodevelopmental model fails to explain many aspects of schizophrenia including the timing of the onset, and the nature of the abnormal perceptions. Furthermore, we do not know why some members of the general population have anomalous experiences but remain well, while others enter the prodrome of psychosis, and a minority progress to frank schizophrenia. We suggest that genes or developmental damage result in individuals vulnerable to dopamine… CONTINUE READING


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The data-gathering bias in the at-risk mental state (ARMS) for psychosis

  • M. Broome, L. Johns, +7 authors P. McGuire
  • Schizophr. Res
  • 2004
Highly Influential
10 Excerpts

The neuropsychology of schizophrenia

  • J. Gray, J. Feldon, J. Rawlins, D. Hemsley, A. Smith
  • Behav. Brain,
  • 1991
Highly Influential
6 Excerpts

The association of inequality with the incidence of schizophrenia— an ecological study

  • J. Boydell, J. van Os, K. McKenzie, R. M. Murray
  • Soc. Psychiatry Psychiatr. Epidemiol
  • 2004
Highly Influential
5 Excerpts

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