What catatonia can tell us about “top-down modulation”: A neuropsychiatric hypothesis

  title={What catatonia can tell us about “top-down modulation”: A neuropsychiatric hypothesis},
  author={Georg Northoff},
  journal={Behavioral and Brain Sciences},
  pages={555 - 577}
  • G. Northoff
  • Published 1 October 2002
  • Psychology, Biology, Medicine
  • Behavioral and Brain Sciences
Differential diagnosis of motor symptoms, for example, akinesia, may be difficult in clinical neuropsychiatry. Symptoms may be either of neurologic origin, for example, Parkinson's disease, or of psychiatric origin, for example, catatonia, leading to a so-called “conflict of paradigms.” Despite their different origins, symptoms may appear more or less clinically similar. Possibility of dissociation between origin and clinical appearance may reflect functional brain organisation in general, and… 

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