What can we learn from real world studies on direct oral anticoagulants?

Direct oral anticoagulants (DOACs) are replacing vitamin K antagonists (VKA) for most patients with atrial fibrillation (AF) and venous thromboembolism. The four currently available DOACs were compared with VKA in phase III randomised controlled trials that collectively included over 100,000 patients. The results show that DOACs, at a fixed dose without… CONTINUE READING