What can we learn about schizophrenia from studying the human model, drug‐induced psychosis?

  title={What can we learn about schizophrenia from studying the human model, drug‐induced psychosis?},
  author={R. Murray and A. Paparelli and P. D. Morrison and Arianna Marconi and M. Di Forti},
  journal={American Journal of Medical Genetics Part B: Neuropsychiatric Genetics},
  pages={661 - 670}
  • R. Murray, A. Paparelli, +2 authors M. Di Forti
  • Published 2013
  • Psychology, Medicine
  • American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
  • When drug‐induced psychoses were first identified in the mid‐20th century, schizophrenia was considered a discrete disease with a likely genetic cause. Consequently, drug‐induced psychoses were not considered central to understanding schizophrenia as they were thought to be phenocopies rather than examples of the illness secondary to a particular known cause. However, now that we know that schizophrenia is a clinical syndrome with multiple component causes, then it is clear that the drug… CONTINUE READING
    52 Citations
    Drug Abuse and Psychosis: New Insights into Drug-induced Psychosis
    • 17
    • Highly Influenced
    • PDF
    Classical hallucinogens as antidepressants? A review of pharmacodynamics and putative clinical roles
    • 69
    • PDF
    The Immune and Metabolic Factors of Schizophrenia
    • 2
    • PDF
    The influence of risk factors on the onset and outcome of psychosis: What we learned from the GAP study
    • 2
    • PDF


    What causes the onset of psychosis?
    • 189
    Recent advances in the phencyclidine model of schizophrenia.
    • 2,702
    Study of a new schizophrenomimetic drug; sernyl.
    • 887
    Schizophrenia: From developmental deviance to dopamine dysregulation
    • 140
    Provocative tests with psychostimulant drugs in schizophrenia
    • 428
    Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial
    • 947
    • PDF
    Serotonergic basis of antipsychotic drug effects in schizophrenia
    • 202
    LSD psychosis or LSD-induced schizophrenia? A multimethod inquiry.
    • 94
    Dopaminergic sensitization: Implications for the pathogenesis of schizophrenia
    • 58
    Cannabis consumption and risk of developing schizophrenia: myth or reality?
    • 14
    • PDF