What are ventilation defects in asthma?

@article{Svenningsen2014WhatAV,
  title={What are ventilation defects in asthma?},
  author={Sarah Svenningsen and Miranda Kirby and Danielle Starr and Harvey O Coxson and Nigel A M Paterson and David G. McCormack and Grace Parraga},
  journal={Thorax},
  year={2014},
  volume={69 1},
  pages={63-71}
}
BACKGROUND Hyperpolarised (3)He MRI provides a way to visualise regional pulmonary functional abnormalities that in asthma are thought to be related to airway morphological abnormalities. However, the exact aetiology of ventilation defects in asthma is not well understood. OBJECTIVE To better understand the determinants of ventilation defects in asthma, we evaluated well-established clinical as well as (3)He MRI and X-ray CT airway measurements in healthy subjects and subjects with asthma… CONTINUE READING
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