• DOI:10.1016/j.steroids.2012.12.011
Corpus ID: 11803629

What are the physiological estrogens?

@article{Baker2013WhatAT,
  title={What are the physiological estrogens?},
  author={M. Baker},
  journal={Steroids},
  year={2013},
  volume={78},
  pages={337-340}
}

M. Baker

Published 2013

Chemistry, Medicine

Steroids

Estradiol (E2) is the principal physiological estrogen in mammals. E2 and its active metabolites, estrone and estriol have a characteristic phenolic A ring, unlike progesterone, testosterone, cortisol and aldosterone, which have an A ring containing a C3-ketone, a Δ(4) bond and a C19 methyl group. Crystal structures of E2 in the estrogen receptor (ER) confirm the importance of the A ring in stabilizing E2 in the ER. However, other steroids, including Δ(5)-androstenediol, 5α-androstanediol and… CONTINUE READING

View on Elsevier

doi.org

Save to Library

Create Alert

Cite

Launch Research Feed