What are the most efficacious treatment regimens for isoniazid-resistant tuberculosis? A systematic review and network meta-analysis

@inproceedings{Stagg2016WhatAT,
  title={What are the most efficacious treatment regimens for isoniazid-resistant tuberculosis? A systematic review and network meta-analysis},
  author={Helen R Stagg and Ross Harris and H-A Hatherell and D Obach and Hongxin Zhao and Naho Tsuchiya and Katharina Kranzer and Vlad Nikolayevskyy and Jusang Kim and Marc Caeroos Isaac Lipman and Ibrahim Abubakar},
  booktitle={Thorax},
  year={2016}
}
INTRODUCTION Consensus on the best treatment regimens for patients with isoniazid-resistant TB is limited; global treatment guidelines differ. We undertook a systematic review and meta-analysis using mixed-treatment comparisons methodology to provide an up-to-date summary of randomised controlled trials (RCTs) and relative regimen efficacy. METHODS Ovid MEDLINE, the Web of Science and EMBASE were mined using search terms for TB, drug therapy and RCTs. Extracted data were inputted into fixed… CONTINUE READING
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