What are the basic functions of microfilaments? Insights from studies in budding yeast

@article{Bretscher1994WhatAT,
  title={What are the basic functions of microfilaments? Insights from studies in budding yeast},
  author={Anthony Bretscher and Betty Drees and Edina Harsay and Diane Schott and Ting Wang},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={126},
  pages={821 - 825}
}
T WENTY-FIVE years ago, F-actin was discovered to be the major component of microfilaments in animal cells (36). Since then, actin has been found in virtually all eukaryotic cells. What functions do microfilaments perform? Studies in animal cells have provided us with a picture of F-actin as the backbone of many structurally and functionally diverse assemblies coexisting within any given cell. Mi-crofilaments are important for cell shape determination, cell motility, and various contractile… CONTINUE READING
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