What Risks Should Be Permissible in Controlled Human Infection Model Studies?

  title={What Risks Should Be Permissible in Controlled Human Infection Model Studies?},
  author={Ariella Binik},
  journal={Public Health Law \& Policy eJournal},
  • A. Binik
  • Published 1 March 2020
  • Biology
  • Public Health Law & Policy eJournal
Controlled human infection model (CHIM) studies involve the intentional exposure of healthy research volunteers to infectious agents. These studies contribute to knowledge about the cause or development of disease and to the advancement of vaccine research. But they also raise ethical questions about the kinds of risks that should be permissible and whether limits should be imposed on research risks in CHIM studies. Two possible risk thresholds have been considered for CHIM studies. The first… 
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