What Are the Precursor and Early Lesions of Peripheral Intrahepatic Cholangiocarcinoma?

  title={What Are the Precursor and Early Lesions of Peripheral Intrahepatic Cholangiocarcinoma?},
  author={Y. Nakanuma and A. Tsutsui and X. S. Ren and K. Harada and Yasunori Sato and M. Sasaki},
  journal={International Journal of Hepatology},
  • Y. Nakanuma, A. Tsutsui, +3 authors M. Sasaki
  • Published 2014
  • Medicine
  • International Journal of Hepatology
  • Cholangiocarcinoma (CC) is divided into distal, perihilar, and intrahepatic CCs (ICCS), and are further subdivided into large bile duct ICC and peripheral ICC. In distal and perihilar CC and large duct ICC, biliary intraepithelial neoplasm (BilIN) and intraductal papillary neoplasm (IPN) have been proposed as precursor lesions. Peripheral ICC, bile duct adenoma (BDA), biliary adenofibroma (BAF), and von Meyenburg complexes (VMCs) are reportedly followed by development of ICCs. Herein, we… CONTINUE READING
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