Wet-surface-enhanced ellipsometric contrast microscopy identifies slime as a major adhesion factor during bacterial surface motility.

@article{Ducret2012WetsurfaceenhancedEC,
  title={Wet-surface-enhanced ellipsometric contrast microscopy identifies slime as a major adhesion factor during bacterial surface motility.},
  author={Adrien Ducret and M P Valignat and Fabrice Mouhamar and T{\^a}m Mignot and Olivier Th{\'e}odoly},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 25},
  pages={
          10036-41
        }
}
In biology, the extracellular matrix (ECM) promotes both cell adhesion and specific recognition, which is essential for central developmental processes in both eukaryotes and prokaryotes. However, live studies of the dynamic interactions between cells and the ECM, for example during motility, have been greatly impaired by imaging limitations: mostly the ability to observe the ECM at high resolution in absence of specific staining by live microscopy. To solve this problem, we developed a unique… CONTINUE READING
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